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MOLECULAR MEDICINE AND COMPUTATIONAL BIOLOGY A001840 2025-2026

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List at least one criteria you would use to select a gRNA candidate designed with CHOPCHOP for a knock-in experiment.
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Match each concept to its correct definition.
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Which statement best defines gene therapy?
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Which statement about recent CRISPR advances is correct?
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Match each vector type to its characteristic.
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In an in vivo gene therapy approach, the vector is delivered directly into the patient’s body.

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Explain one major limitation of viral vectors in gene therapy.
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List at least one reason why nucleoside modifications improved the function and safety of mRNA vaccines.

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Which vector is most suitable for long-term gene expression in non-dividing neurons?
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mRNA vaccines integrate into the host genome.
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