They are used in synaptic signaling and include neurotransmitters, cytokines and hormones

They are used in non-synaptic signaling and have long lasting effects and long survival times

They are used in synaptic signaling and have short survival times and short lasting effects

They are used in non-synaptic signaling and have short lasting effects and short survival times

They are used in synaptic and non-synaptic signaling and have long lasting effects

always membrane-bound.

always linked to G-proteins and 2nd messengers.

intracellular receptors that either bind to DNA or activate 2nd messengers.

intracellular receptors that bind to DNA.

always membrane-bound and form ion channels.

Neither type of receptor allows electrotonic flow of current

Receptors for lipid-soluble chemical signals, but not those for water-soluble signals, are hemichannels contributed by both cells

Both types of receptor allow electrotonic flow of current

Receptors for water-soluble chemical signals, but not those for lipid-soluble signals, are hemichannels contributed by both cells

Receptors for lipid-soluble chemical signals, but not those for water-soluble signals, allow rapid electrotonic current flow

It causes activation of G proteins

It causes an opening of the water-filled pore

It causes a change in shape that leads to cell responses

It results in specificity and affinity between chemical and receptor

It causes an opening of ion channels

Opening or closing of ion channels

Activation of tyrosine kinase

Activation of G-proteins

Downstream production of 2nd messengers

DNA transcription via receptor binding

Is that mediated by receptors that control the trans-membrane movement of ions

Produces 2nd messengers

Activates Tyrosine Kinase receptors

Acts through intra-cellular receptors that can modulate the DNA

Acts through membrane-bound receptors that activate G proteins

Modulate the on-going ionic movement across the membrane

Increase the on-going ionic movement across the membrane

Allow in ions to activate G proteins to produce fast cellular responses

Allow in ions to produce fast cellular responses

Decrease the on-going ionic movement across the membrane

produce faster responses than ionotropic receptors

will never share the same ligand as an ionotropic receptor

are composed of 7 protein subunits

can act through the same second messenger to have different effects in different cell types

that respond to the same ligand are all coupled to the same type of G protein