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BMS/GNA2042 - Human Genetics - S2 2025

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Does the result of the χ2 test support your hypothesis? Explain why it does / does not. If the χ2 test does NOT support your hypothesis, suggest an alternative genetic hypothesis that may account better for the class data (you do not need to repeat the χ2 test).

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Another Drosophila gene, apterous, also affects early wing development, with apterous mutants having an identical phenotype to vestigial mutants (i.e. both mutants have small and deformed wings). A similar experiment to our one for vestigial and curved was performed with vestigial and apterous instead, the results indicated that the F1 progeny were wild-type. What phenotypic ratio would you expect in the F2?

Consider the different types of gene interactions.

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Thinking about how wings are formed in Drosophila, speculate on the basis of the vestigial and curved phenotypes, and any interactions between them that you may have observed.

Which of the following is most likely correct based on your analysis of the data?

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Are there any sex differences within classes in the F1? (Hint: look to see if there are different wing phenotypes present between male and female flies).

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What term describes the phenomenon when the expression of one gene masks the expression of another?

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What type of allele is often detected as a distortion in segregation ratios, where one class of expected progeny is missing?

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