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BMS/GNA2042 - Human Genetics - S2 2025

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Does the result of the χ2 test support your hypothesis? Explain why it does / does not. If the χ2 test does NOT support your hypothesis, suggest an alternative genetic hypothesis that may account better for the class data (you do not need to repeat the χ2 test).

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Thinking about how wings are formed in Drosophila, speculate on the basis of the vestigial and curved phenotypes, and any interactions between them that you may have observed.

Which of the following is most likely correct based on your analysis of the data?

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Using the CLASS DATA of the F2 progeny, the genetic hypothesis that best fits this data is:

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Another Drosophila gene, apterous, also affects early wing development, with apterous mutants having an identical phenotype to vestigial mutants (i.e. both mutants have small and deformed wings). A similar experiment to our one for vestigial and curved was performed with vestigial and apterous instead, the results indicated that the F1 progeny were wild-type. What phenotypic ratio would you expect in the F2?

Consider the different types of gene interactions.

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Are there any sex differences within classes in the F1? (Hint: look to see if there are different wing phenotypes present between male and female flies).

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The color of sunflower pollen can be orange, yellow, or white-cream. Crosses reveal that true-breeding orange is dominant to both yellow and white-cream. However, a cross between true-breeding white-cream and yellow plants produced F1 plants with orange pollen. The F2 populations of this cross resulted in a ratio of nine orange: four white-cream: three yellow. What type of interaction do these results suggest?

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You have read that in guinea pigs, black fur is dominant to white fur. You are surprised then when your two white guinea pigs have all black F1.  When you cross the F1, you observe 9:7 black:white. How do you best explain this?

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