Which of the common sex chromosome aneuploidies would show a Barr body test result that does not correctly reflect the phenotypic sex of the individual?

Note: incorrect answers will lose a percentage of the marks possible for this question.

Which of the following factors is thought to contribute to the changes in the risk of Down syndrome associated with maternal age?

Why is aneuploidy of the sex chromosomes less debilitating than aneuploidy of even the smallest autosomes?

Note: multiple responses are correct, please choose the best answer(s), incorrect answers will lose a percentage of the marks possible for this question.

Based on the information you have been given in this lab, and from your calculations, what do you think is the most likely association between the CCR5-Δ32 allele and Smallpox and bubonic plague? Hint: consider

homozygous and heterozygous genotypes.

While you cannot directly calculate the selection coefficient, can you infer which disease might have exerted stronger selection based on the observed deviations from HWE?