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BPS3012 Applied Pharmaceutical Science: From Concept to Market S2 2025

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Proteasomes possess protease activity, which catalyse the hydrolysis of what type of compounds?

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The modification of a histone lysine will influence the binding of a histone peptide to DNA. Which of the following is not a method of histone lysine modification?

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Image failed to load: Histone methylation

In the figure above, identify the two lysine residues that are mutually exclusive with respect to histone regulation. In other words, presence of methyl substition on one lysine, prevents methylation of the other.

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The enzymes that catalyse histone acetylation are called

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Which two residues of the bromodomain does an acetyllysine of a histone bind to?

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What is chromatin?

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The most common epigenetic modification to DNA is methylation of: 

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