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2025-MED1BSF(BU-2) - FOUNDATIONS OF BIOMEDICAL SCIENCE

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What is the concentration (in mM) of the ketamine in a supplied vial that contains 200 mg in 2 mL? (the molecular weight of ketamine is 237.7 g/mole).

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A patient requires a dose of 40mg of ketamine.  For treatment, a vial of ketamine (200 mg in 2 mL) is diluted to 20 mL for administration.

What volume of the diluted ketamine

solution should be administered to the patient? (enter value only, will be assumed to be in mL)

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A patient (20 kg) being treated by a paramedic

needs to be intubated, following sedation with ketamine at a dose of 1.5 mg/kg. 

What dose (in mg) should be administered?  (enter number only, units will be assumed to be in mg)

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What is the  dosage of elemental iron ingested if a patient swallows 8 tablets of iron supplement (425 mg/tablet) with compositions of elemental iron = 25% w/w?

 

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A patient with a suspected paracetamol overdose returns a serum paracetamol concentration of 600 μmol/L, four hours after admission.

As the treating clinician (using the nomagram below), you would commence treatment. (True = Yes/False = No)

 

 

 

 

 

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A solution has a paracetamol concentration of 950 μg/L.  Choose from the list below the equivalent concentration in mg/dL.

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In the video from Ray the paramedic he discussed why it is important to have confidence in maths.

Why is a knowledge of concentration unit and calculations important in a pressured clinical setting.

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An aliquot (20 mL) of a Na2SO4 stock solution is made up to 200 mL with water.  The final concentration of Na2SO4 in the diluted solution is 50 mM.  What was the concentration of Na2SO4 in the stock solution?

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An aliquot (20 mL) of 150 mM Na2SO4 is added to 280 mL water.  What is the final concentration of Na2SO4 in the diluted solution?

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A stock solution of 2.0 M Tris-HCl buffer needs to be diluted to a final volume of 220 mL and final concentration of 150 mM.  What volume of stock solution is required?

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