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Although oral administration is convenient to the patient, the drug is completely destroyed by the digestive juices.
If two medications produce less than an additive effect, they are called synergistic.
Vomiting reflex can be stimulated by the cerebrum, especially when a person experiences pain, smells something repulsive, or sees something ugly (for some patients it can be blood).
The vomiting center is located within cerebellum, namely medulla oblongata.
While vomiting, the heart rate goes down.
The epiglottis does not close while a person is vomiting.
In motion sickness, vestibular nuclei are not stimulated.
While vomiting, the lower esophageal sphincter relaxes, the diaphragm and abdominal muscles contract.
Muscarinic receptor antagonists block the receptors in the , even though they can trigger dry mouth blurry vision, and drowsiness.
The vomiting center contains muscarinic receptors which, when are stimulated, trigger vomiting.