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A 63-year-old man comes to the physician for a follow-up evaluation of chronic, retrosternal chest pain. The pain is worse at night and after heavy meals. He has taken medicines to reduce the production of stomach acids for several months without any relief from his symptoms. An upper endoscopy shows changes in the distal esophagus and in the area above the gastro-oesophageal junction. A biopsy of the distal esophagus shows simple columnar epithelium with goblet cells, which does not occur normally here. Which type of epithelium should normally occur here?
A 15-year-old girl had her tongue pierced unprofessionally by her friend. Unfortunately, this unprofessional execution led to an infection of the tongue, as well as the sublingual salivary gland located nearby. Which of the following describes the histological description of this gland?
A 36-year-old man presents with abdominal pain and gastroesophageal reflux (connected with heartburn). An endoscopic exam reveals gastric ulcers. A serum analysis reveals increased levels of gastrin, a hormone that stimulates the release of gastric acid from the parietal cells of gastric glands. Which of the following cell types is the source of the hormone?
A 64-year-old man with diverticular disease comes to the emergency department because of painless rectal bleeding, dizziness, and lightheadedness for 2 hours. His temperature is 37.8°C, his pulse is 120/min, his respirations are 23/min, and his blood pressure is 83/61 mmHg. His skin and mucous membranes are pale. Physical examination shows bright red rectal bleeding. Endoscopic hemostasis is performed. On the base of liver enzymes elevation together with hemoglobin decrease in plasma, we assume that hypoxic damage of hepatocytes has occurred, especially in zone III (near the central vein). Which unit of the liver parenchyma consists of 3 zones, one of which is the zone around the central vein?
A 45-year-old patient comes to the dental emergency at night for an acute toothache. Previously, the given tooth was more sensitive to cold or warm stimuli. Now the pain is throbbing and constant, and cold stimuli tend to relieve it. Common analgesics are ineffective. The patient is diagnosed with acute pulpitis, inflammation of the dental pulp. The dental pulp is mainly made up of loose connective tissue, which is also the reason why inflammation spreads easily here. What important type of cell is also part of the pulp chamber?
A 22-year-old patient presents for a colonoscopy to confirm a diagnosis of Crohn's disease or ulcerative colitis. He has been suffering from crampy abdominal pain with watery diarrhea with admixture of blood and mucus for several weeks. During the endoscopy, a typical picture of mucosal damage by these autoimmune inflammations is described and a biopsy is taken for histological examination, which finally establishes the diagnosis of ulcerative colitis. Ulcerative colitis is a rare autoimmune type of inflammation of the digestive system that typically affects the mucosa and submucosa of the rectum and colon. Which of the descriptions offered describes the normal appearance of the colonic mucosa?
A 59-year-old lifelong alcoholic man presents with fever and abdominal pain that radiates to his back. A physical exam reveals that his abdomen is tender in the midline between the bottom of his ribs and his umbilicus. Blood tests reveal elevated levels of pancreatic enzymes, and ultrasound suggests inflammation of the pancreas or pancreatitis. The elevated pancreatic enzymes are from which of the following cell types?
A 44-year-old man comes to the physician because of a 6-month history of persistent cough with yellow mucus and worsening shortness of breath. One year ago, he had similar symptoms that lasted 4 months. He has smoked two packs of cigarettes daily for the past 20 years. Goblet cells and glands typical for the respiratory tract are involved in the production of mucus. What type of glands do we find here? (See figure)
A 9-year-old boy is brought to the physician by his mother because of a few-day history of fever and cough. He has had similar episodes of inflammation of the respiratory tract with fever, cough, and runny nose with the presence of thick, colored mucus in the past. The most likely cause of recurrent infections in this patient is a dysfunction of which of the following cell types?
An investigator studying new drug delivery systems administers an aerosol containing 10 μm sized particles to a healthy subject via a special mask. These particles are found to deposit on the surface of the respiratory tract with a pseudostratified epithelium. Which of the following mechanism is the most likely way of clearance of the particulate matter in this subject?