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After repeated severe pneumonia, often accompanied by otitis media, the young paediatrician can no longer think of many options for further examinations of the young 5-year-old patient. After a thorough immunoassay, which reveals no deficiency in cellular or antibody immunity, the tissue sample is sent for further electron microscopic examination. This examination demonstrates the rare Kartagener syndrome, which leads to dysfunctional cilia. The cilia are present, but due to the lack of a molecular motor, they are immobile and cannot perform their cleansing role, which leads, among other things, to frequent infections with a more severe course. What is the name of the molecular motor present between the microtubules in the cilia?
A 58-year-old man with colorectal cancer comes to the physician for a follow-up examination 6 weeks after undergoing resection for the treatment of colorectal cancer. Physical examination shows a clean, nontender scar on the lower abdomen. The physician recommends an adjuvant treatment with cytostatics. Which of the following types of cells are most affected by this therapy?
The teacher wants to demonstrate a typical serous gland to the students in practical exercises focused on the glandular epithelium. However, he does not have much time to think about it, because he has more tasks to complete. Which slide should he choose to show the students typical serous acini?
During a routine preventive examination, a 65-year-old patient is found to have an asymmetrically enlarged liver. The patient himself admits that he drinks alcohol regularly and is therefore referred for an ultrasound examination of the liver. The examination reveals a prominent mass in the right lobe of the liver and a biopsy shows hepatocellular carcinoma. After further investigations, the patient undergoes surgery during which the tumour is removed. To confirm that the entire tumour has been removed, including a sufficient margin of surrounding healthy liver tissue, the resection is sent to pathology. What epithelium makes up the rim of healthy liver tissue?
A 26-year-old woman who is known to be 6 weeks pregnant presents with severe abdominal pain. An ultrasound is performed and demonstrates a corpus luteum cyst. The following figure is obtained from the biopsy of the cyst. What is the function of the organelle indicated by the arrow?
A 4-year-old boy has recently returned from a holiday abroad and has now arrived now at the Clinic of Infectious Diseases with his parents due to severe dehydration caused by diarrhoea. The causative bacterium is , which disrupts the structure of one type of intercellular junctions – tight junction = zonula occludens. This physiologically prevents the passage of fluid between cells – the so-called paracellular route. Disruption of these tight junctions results in fluid loss into the lumen of the gastrointestinal tract. Where can we find these tight junctions on cells?
An investigator is studying the function of the endoplasmic reticulum in genetically modified lymphocytes. One specific gene is removed. Its function is to facilitate the binding of ribosomes to the endoplasmic reticulum. As a result of this genetic modification, the binding of ribosomes to the ER was disrupted. Which of the following processes describes the normal function of this organelle?
A 54-year-old man has had issues with increased urinary frequency. More recently, he reports that he has blood in his urine. Imaging shows a mass growing into the lumen of the bladder, which is biopsied. Normal tissue adjacent to the mass will be of which type of epithelium?
The student is asked about the difference between the basement membrane and the basal lamina during the histology exam. Until now, he thought that the two terms were identical. Could you advise him what the difference is between these two structures?
Which of the following would be a presenting symptom in an infant born with dysfunction of the structures in the photomicrograph?