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علم الأدوية 1 - الامتحان الموحد
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A 68-year-old woman is brought to the emergency department for treatment of a myocardial infarction. She is currently taking clopidogrel (antiplatelet agent) and aspirin daily, as well as omeprazole (potent CYP inhibitor) for heartburn. Which of the following is the most likely contributor to her myocardial infarction today?
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A 64-year-old female patient (60 kg) is treated with experimental Drug A for type 2 diabetes. Drug A is available as tablets with an oral bioavailability of 90%. If the Vd is 2 L/kg and the desired steady-state plasma concentration is 3.0 mg/L, which of the following is the most appropriate oral loading dose of Drug A?
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A 60-year-old patient started a new antihypertensive medication. His blood pressure is well controlled, but he complains of fatigue, drowsiness, and fainting when he gets up from the bed (orthostatic hypotension). Which of the following drugs is he most likely taking?
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A 60-year-old female who had a cancerous growth in the neck region underwent radiation therapy. Her salivary secretion was reduced due to radiation and she suffers from dry mouth (xerostomia). Which drug would be most useful in treating xerostomia in this patient?
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A 59-year-old non-Hispanic white patient presents for treatment of hypertension. His past medical history also includes diabetes, hyperlipidemia, and hypertension. The patient's blood pressure is 150/93 {both today and at the last visit). Which is a recommended initial therapy to treat hypertension in this patient?
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A 55-year-old woman is brought to the emergency department because of seizures. She has a history of renal disease and currently undergoes dialysis. She receives an intravenous infusion of antiseizure Drug X. Which of the following is likely to be observed with use of Drug X in this patient? Half-life Dosage
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A 55-year-old male with kidney stones needs a medication to decrease urinary calcium excretion. Which diuretic is best for this indication?
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A 55-year-old non-Hispanic black male has hypertension. His past medical history also includes diabetes and hyperlipidemia. According to the ACC/AHA guidelines, which among the choices represents the most appropriate blood pressure goal for the patient?
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A 50-year-old male who is noncompliant with medications was recently diagnosed with chronic obstructive pulmonary disease (COPD). His physician would like to prescribe an inhaled anticholinergic that is dosed once or twice daily. Which drug is most appropriate for this patient?
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A 50-year-old male was in anaphylactic shock after being stung by a hornet. The medical team tried to reverse the bronchoconstriction and hypotension using epinephrine; however, the patient did not fully respond to the treatment. The patient's wife mentioned that he is taking a prescription medication for blood pressure. Which medication is he most likely taking that contributed to a reduced response to epinephrine?
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