Rotenone inhibits the flow of electrons from FMN to coenzyme Q. Discuss how this affects oxidative phosphorylation.

Energy Transformation

The major purpose of the electron transport chain is to provide the energy for the synthesis of ATP from ADP and inorganic phosphate (Pi).

The energy is provided by:

There are few ways to regulate the process of glycolysis. The first of these is the regulation of the enzymes involved in glycolysis.

There are three key enzymes that are involved in the regulation of glycolysis. What are they?

During intense exercise we feel a muscle ache? What causes this? 

The second way to regulate glycolysis is by changing the types of enzymes involved in glycolysis in different types of cells.

For example, hexokinase is the first enzyme of the glycolysis pathway in most cells of the body, but glucokinase is used by liver cells instead. They both produce the same end product, glucose-6-phosphate.

Glucokinase has a low affinity for glucose compared to hexokinase which has high affinity to glucose. Explain the reasoning behind this.

Hexokinase	Glucokinase

What are advantages of multi-enzyme complexes such as the pyruvate dehydrogenase? 

Yeast seems to consume far more sugar when they are growing anaerobically compared to aerobically.

Using your understanding of the amount of energy produced through glycolysis, explain this scenario in the text box below.

How many chiral carbon atoms are found in this sugar?

What is the main energy reserve in animals and humans?