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BIOC2181-Fundamentals of Biochemistry T3 2025

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True or False?

The breakdown of dietary proteins begins in the mouth.

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What molecule is added as a tag to mark the proteins for degradation?

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To synthesise proteins, the body requires amino acids.

What are two major sources of amino acids for protein synthesis?

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True or False?

Fatty acid synthase subunits must form an antiparallel dimer in order for it to carry out its function.

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True or False?

Newly synthesised fatty acids can be stored as triglycerides or synthesised into phospholipids.

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True or False?

Fatty acid synthesis is the complete reversal of β-oxidation. 

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True or False?

Fatty Acid synthase contains prosthetic groups that help to attach the intermediates of fatty acid synthesis and allow them to move from one catalytic site to another. This allows for the elongation of the fatty acid.

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True or False?

Fatty acid synthase is a large complex enzyme with several distinct catalytic regions.

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Ketone body formation is a three-step process. At the end of the third step, the body produces acetoacetate. Acetoacetate can be reduced to form β-hydroxybutyrate. Acetoacetate can also undergo slow spontaneous decarboxylation to form acetone. These ketone bodies can be used to generate energy.

Ketone bodies utilisation

  • β-hydroxybutyrate is first converted to Acetoacetate. This reaction produces the reduced cofactor ___________.
  • Acetoacetate then goes through several more steps to ultimately produce two molecules of acetyl CoA which will enter the TCA cycle to help produce ATP through oxidative phosphorylation.
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Which statement about fatty acid synthesis is incorrect?

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