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Biophase or Indirect response (IDR) model? Which one would you choose for each o...

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Biophase or Indirect response (IDR) model? Which one would you choose for each of the following and why?

  • Effect of propofol on general anaesthesia
  • Effect of alendronate on biomarkers that describe bone turnover
  • Effect of γ-Secretase modulators on pathogenic amyloid-β peptide production in Alzheimer’s disease
  • Effect of sodium glucose cotransporter 2 inhibitors (SGLT2i) on fasting plasma glucose
  • Effect of morphine on the EEG in a rat study
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