A dermatologist examines a patient with
several dysplastic nevi and explains that melanoma risk is higher in
individuals with many atypical moles because these lesions may already contain
genetic alterations in melanocytes.

Why do dysplastic nevi increase the
likelihood of melanoma developing?

Question

A dermatologist examines a patient with
several dysplastic nevi and explains that melanoma risk is higher in
individuals with many atypical moles because these lesions may already contain
genetic alterations in melanocytes.

Why do dysplastic nevi increase the
likelihood of melanoma developing?

Accepted Answer

They
represent melanocyte populations that may already carry mutations that can
progress to malignancy

Answer

They arise from
chronic inflammation in the skin that permanently activates keratinocyte growth
signals

Answer

They increase the
rate of melanin production, which directly stimulates melanocyte proliferation

Answer

They prevent normal
apoptosis in keratinocytes, allowing abnormal skin cells to accumulate

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A dermatologist examines a patient with several dysplastic nevi and explains th...

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