Your company has performed a PK study in mice (weight 25 g) with the new antibio...
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Your company has performed a PK study in mice (weight 25 g) with the new antibiotic. Protein binding is 99%. For successful inhibition of bacterial growth of P. aeruginosa, 25% of the max. effect are required.
5. What is the expected duration of effect of a 1 mg/kg IV bolus of your drug in the mouse against a bloodstream infection caused by P. aeruginosa?
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