A 38-year-old woman, who was diagnosed with systemic lupus erythematosus (SLE) 3 years ago, comes to her physician with a complaint of

facial swelling and decreased urination that she first noticed 2 weeks ago. She currently takes azathioprine and a corticosteroid. Her

vital signs show blood pressure - 150/90 mm Hg, pulse - 91/min., temperature - 36.8OC and respiratory rate - 15/min. On physical

examination, the doctor notices erythematous rash on her face exhibiting a butterfly pattern. The laboratory studies reveal

hypercholesterolemia, hypertriglyceridemia and proteinuria. Which of the following is the most likely mechanism of SLE’s complication

in this patient?

Question

A 38-year-old woman, who was diagnosed with systemic lupus erythematosus (SLE) 3 years ago, comes to her physician with a complaint of 
 
facial swelling and decreased urination that she first noticed 2 weeks ago. She currently takes azathioprine and a corticosteroid. Her 
 
vital signs show blood pressure - 150/90 mm Hg, pulse - 91/min., temperature - 36.8OC and respiratory rate - 15/min. On physical 
 
examination, the doctor notices erythematous rash on her face exhibiting a butterfly pattern. The laboratory studies reveal 
 
hypercholesterolemia, hypertriglyceridemia and proteinuria. Which of the following is the most likely mechanism of SLE’s complication 
 
in this patient?

Answer

Decrease in renal blood flow (ischemic nephropathy)

Answer

Increased plasma oncotic pressure

Answer

Acute infection of the kidney

Answer

Immune complex-mediated glomerular disease

Answer

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A 38-year-old woman, who was diagnosed with systemic lupus erythematosus (SLE) 3...

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