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Bruton’s tyrosine kinase (BTK) is a cytoplasmic signalling molecule downstream ...

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Bruton’s tyrosine kinase (BTK) is a cytoplasmic signalling

molecule downstream of the B cell receptor. Inhibitors of BTK are clinically

effective in treating certain B cell malignancies by interfering with survival

and growth pathways.

Which physiological function for BTK best

explains why inhibition of this kinase is effective against B cell cancers?

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