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Hypoxia can be caused by which of the following?
1. A decreased saturation of oxygen in the blood due to carbon monoxide attached to the haemoglobin.
2. Low partial pressure of oxygen in the atmosphere when flying at high altitudes without pressurisation and
supplemental oxygen.
3. Malfunction of the body cells to metabolise oxygen.
4. Blood pooling in the lower extremities due to inertia (+Gz).