Which combination best explains H. pylori –induced ulcer formation and cancer risk, and why standard acid-reduction therapy alone often fails to cure the infection?

Question

Which combination best explains  H. pylori –induced ulcer formation and cancer risk, and why standard acid-reduction therapy alone often fails to cure the infection?

Answer

H. pylori  secretes large amounts of acid that erode mucosa, and PPIs fail because the bacterium becomes dormant at high pH

Answer

H. pylori  causes ulcers by blocking mucus secretion, and PPIs fail because they stimulate bacterial motility.

Answer

H. pylori  survives gastric acid with urease, disrupts epithelial signaling through CagA and VacA toxins, and induces chronic inflammation; PPIs alone fail because the infection persists unless the bacterium is eradicated with antibiotics.

Answer

H. pylori  integrates into host DNA, activating oncogenes, and PPIs fail because they inactivate gastric macrophages.

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Which combination best explains H. pylori –induced ulcer formation and cancer r...

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