Consider the following two ionisable groups positioned close to each other within a protein structure:

A lysine side chain (pKa = 10.5)
An aspartic acid side chain (pKa = 3.7)

Based on the pKa values of these functional groups and their charge states when they are ionised, select the correct statement below.
[Note that these statements are specifically referring to the attraction or repulsion of ionic interactions between these groups ]

Question

Consider the following two ionisable groups positioned close to each other within a protein structure: 
 
 A lysine side chain (pKa = 10.5) 
 An aspartic acid side chain (pKa = 3.7) 
 
 Based on the pKa values of these functional groups and their charge states when they are ionised, select the  correct statement  below. 
 [Note that these statements are specifically referring to the attraction or repulsion of  ionic interactions between these groups ]

Answer

In an aqueous solution at pH 2, these two groups are expected to attract each other.

Answer

In an aqueous solution at pH 5, these two groups are expected to repel each other.

Answer

In an aqueous solution at pH 2, these two groups are expected to repel each other.

Answer

In an aqueous solution at pH 12, these two groups are expected to repel each other.

Answer

In an aqueous solution at pH 12, these two groups are expected to attract each other.

Answer

In an aqueous solution at pH 5, these two groups are expected to attract each other.

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Consider the following two ionisable groups positioned close to each other withi...

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