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Following the activation of a naïve T cell, the cytokine IL-2 is produced. In this process:
The T cell produces an IL-2 receptor with much stronger affinity
IL-2 binds the IL-2 receptor on neighbouring T cells promoting their differentiation into T helper cells
IL-2 binds the IL-2 receptor on the antigen expressing dendritic cell to enhance the presentation of peptide
IL-2 promotes the migration of the T cell towards the germinal centre
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