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Shown below is a schematic diagram representing the primary structure of an integral membrane protein that traverses a cell membrane 4 times.
"N" and "C" represent the N- and C-termini of the protein.
Hydrophobic (red) and polar (blue) regions are colour coded.
When intact cells containing this protein in the membrane are treated with trypsin, the protein backbone is cleaved at the positions indicated by arrows.
Which regions of this protein are expected to protrude on the cytoplasmic side of the membrane?