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A 70 kg 45-year-old man presents 4 hours following an ingestion of 20x5mg oxycodone. In your ED, he is drowsy but rousable, HR 70 bpm, BP 110/70, RR 6/min, O2 sat 90% RA, GCS 8 (E1V2M5).
What is the most appropriate treatment for this patient?