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A 74-year-old man was admitted to the hospital for treatment of heart failure. H...
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A 74-year-old man was admitted to the hospital for treatment of heart failure. He received 160 meg of digoxin intravenously, and the plasma digoxin level was 0.4 ng/ml. If the desired plasma concentration of digoxin for optimal therapeutic activity in heart failure is 1.2 ng/ml, and the patient has an estimated Vd of 400 L, calculate the additional dose of digoxin needed for this patient to achieve the desired plasma concentration.
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