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A larger than normal load of Na+ at the macula produces ...
pressure-induced natriuresis
a long-term positive feedback on GFR (increased) and negative feedback on blood pressure (lowered)
hyperpolarization of the macula cells and depression of the RAAS system
swelling of macula cells, release of ATP and decrease in GFR by indirect constriction of the afferent arteriole
a rapid (<1 min) negative feedback on GFR (tubulo-glomerular feedback)
depolarisation of the macula cells, release of prostaglandins and activation of the RAAS system
swelling of macula cells, release of ATP and increased diuresis by preferential contraction of the efferent arteriole
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