Mechanism of action of MPP+
You should have observed that oxygen consumption resumed upon the addition of succinate. This would suggest that:
(There are two correct answers)

Question

Mechanism of action of MPP+ 
 You should have observed that oxygen consumption resumed upon the addition of succinate. This would suggest that:  
 (There are two correct answers)

Accepted Answer

Succinate feeds electrons into the electron transport chain at a point below the site of action of MPP+.

Accepted Answer

MPP+ is a respiratory chain inhibitor that blocks Complex 1, the first electron acceptor in the electron transport chain.

Answer

For oxygen consumption to occur in the presence of MPP+, both glutamate and succinate are required as substrates.

Answer

Succinate interacts with MPP+ and inactivates it.

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Mechanism of action of MPP+ You should have observed that oxygen consumption r...

Mechanism of action of MPP+

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