Although the 2009 H1N1 influenza virus was novel, many
infected individuals experienced mild illness, and overall mortality was lower
than initially predicted.

Which factor most plausibly contributed to this relatively
limited clinical impact?

Question

Although the 2009 H1N1 influenza virus was novel, many
infected individuals experienced mild illness, and overall mortality was lower
than initially predicted.

Which factor most plausibly contributed to this relatively
limited clinical impact?

Accepted Answer

Partial
immunity from exposure to antigenically related influenza strains in the past

Answer

The
infection stimulated only antibody‑mediated immunity without cellular responses

Answer

The
virus was poorly adapted to infect human cells

Answer

An
unusually weak innate immune response that prevented inflammation

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Although the 2009 H1N1 influenza virus was novel, many infected individuals expe...

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