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The di-acid form of HEPES is shown below.

The functional group indicated as B has the lower pKa value and is a stronger acid than functional group A.

Explain briefly, with reference to the molecular structure, why this is so.

Die di-suurvorm van HEPES word hieronder getoon.

Die funksionele groep wat as B aangedui word het die laer pKa-waarde en is 'n sterker suur as funksionele groep A.

Verduidelik kortliks, met verwysing na die molekulêre struktuur, hoekom dit so is. 

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