Large scale screening to find mice with cardiac defects using a deliberate mutagenesis approach:
Choose the CORRECT option below:

Question

Large scale screening to find mice with cardiac defects using a deliberate mutagenesis approach: 
 Choose the  CORRECT  option below:

Answer

Requires the insertion of a selectable marker within the genes of interest

Answer

Will only generate dominant phenotypes

Answer

Involves injection of DNA constructs that direct cardiac expression into the pronuclei of fertilised mouse embryos

Answer

Requires the use of homologous recombination

Answer

Involves a forward genetic approach to determine the mutated genes responsible for phenotypes

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