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In contrast to the somatic cell, embryonic genome has several unique features:
it is physiologically polyploid, undergoing to diploidization due to mitotic reduction of blastomeres
it is created in the zygote, after sperm penetreation to the egg, along with the syngamy of maternal and paternal pronuclei
it is inactive till embryonic genome activation at 8-16-cell stage
it is predominantly condensed in heterochromatin and, therefore, it is silenced and transcriptionally inactive
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