Josh suffers from anxiety, which is treated effectively with alprazolam. Josh develops arthritis and is given a course of Dexamethasone for treatment. Dexamethasone is a known inducer of p-glycoprotein activity and Alprazolam is a known substrate for p-glycoprotein.
Considering josh’s treatments for anxiety and arthritis, the most likely result of increased p-glycoprotein activity is?

Question

Josh suffers from anxiety, which is treated effectively with alprazolam.  Josh develops arthritis and is given  a course of Dexamethasone for treatment. Dexamethasone is a known inducer of p-glycoprotein activity and Alprazolam is a known substrate for p-glycoprotein.  
 Considering josh’s treatments for anxiety and arthritis, the most likely result of  increased  p-glycoprotein activity is?

Accepted Answer

an increase in anxiety-related symptoms

Answer

enhanced oral absorption of both drugs

Answer

a decrease in arthritic symptoms

Answer

increased plasma concentrations of alprazolam

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Josh suffers from anxiety, which is treated effectively with alprazolam. Josh d...

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