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A new antibiotic against difficult to treat bacteria has been studied in patients with a wide range of renal functions. The graphs show the probability of attaining the PK/PD target (PTA) of 50% fT>MIC for two different dosage regimens. The PTA profiles are presented for three different groups stratified by creatinine clearance (CLCR, mL/min). Interpret the graphs and discuss what they tell you about dosing of future target patient populations with this new antibiotic.
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