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What contributes the largest amount of diversity in the lymphocyte antigen receptors?
The de novo (new) generation of receptors with each cell division in the bone marrow (BCR) or thymus (TCR)
The de novo (new) generation of receptors in response TLR stimulation by microbes
Recombination of the V(D)J gene segments encoded in the genome
Altering the nucleotides that are found between the V(D)J segments of the receptors
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