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Genomic surveillance shows that SARS‑CoV‑2 continues to accumulate mutations du...

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Genomic surveillance shows that SARS‑CoV‑2

continues to accumulate mutations during global circulation. Many mutations

affect the spike protein, particularly regions involved in immune recognition,

while genes involved in core replication remain highly conserved. Variants with

altered antigenic profiles repeatedly emerge and replace earlier strains.

Given prolonged global circulation in humans,

what long‑term pattern is most likely?

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