The T cell receptor on T cells can interact with MHC. The MHC is associated with presenting peptides but in the context of T cell development in the thymus and positive selection:

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The TCR is interacting with MHC that is presenting self-peptides

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The TCR interact with MHC that are not presenting any peptide

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The TCR does not need to interact with MHC

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The TCR is interacting with MHC that is presenting pathogen associated peptides

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The T cell receptor on T cells can interact with MHC. The MHC is associated with...

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