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Unlike basal cell carcinomas (BCCs) which rarely metastasise, squamous cell carc...

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Unlike basal cell

carcinomas (BCCs) which rarely metastasise, squamous cell carcinomas (SCCs) frequently

metastasise and migrate from the skin to other parts of the body. Metastasis

has been linked to reduced cadherin expression. Explain how reduced cadherin

expression in SCCs impacts junctional complexes and enables metastasis. (2-3

sentences) (2 marks)

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