What metabolic adaptation best explains why weight-cycled (yo-yo dieted) subjects experience accelerated weight regain when re-exposed to a high-fat diet?

Question

Accepted Answer

Weight cycling reduces feed efficiency and lowers total energy expenditure, driven in part by reductions in core body temperature and voluntary locomotor activity.

Answer

Weight
cycling permanently elevates resting energy expenditure, causing extreme
metabolic stress that triggers compulsive caloric overconsumption.

Answer

Weight cycling expands total brown fat thermogenesis, which suppresses basal metabolic rate and forces excess dietary glucose into hepatic glycogen pools.

Answer

Weight cycling increases voluntary locomotor activity, which paradoxically triggers compensatory hyperphagia and increased muscular efficiency.

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What metabolic adaptation best explains why weight-cycled (yo-yo dieted) subject...

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