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A 40-year-old female patient presents with mild anemia and reticulocytosis (incr...

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A 40-year-old female patient presents with mild

anemia and reticulocytosis (increased number of reticulocytes in the blood),

which worsens intermittently. In addition, splenomegaly and icterus (yellow

discoloration of the sclera and mucous membranes) are present during physical

examination. A blood smear was performed for these non-specific symptoms and it

was evident by looking at it that some of the erythrocytes lacked central

pallor. The diagnosis is hereditary spherocytosis, a genetic disease caused by

a defect in the gene for the structural proteins of the erythrocyte

cytoskeleton and membrane. The surface of the erythrocyte is reduced relative

to its internal volume, causing a change in shape from biconcave to

spherical. What are the names of the basic structural proteins of the

erythrocyte membrane cytoskeleton?

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