What is the overall significance of the discovery of microRNA and its role in gene regulation, which motivated the Nobel prize for Medicine 2024?

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It revealed a previously unknown aspect of gene regulation that is essential for all complex life forms

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It showed that the regulation of gene activity is a relatively simple and straightforward process

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It provided a new tool for understanding the basic mechanisms of gene expression

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It demonstrated the importance of transcription factors in controlling cellular development and function

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