Leptin is secreted from adipose tissue and is a key hormone involved in the long-term regulation of body weight. Select the CORRECT response regarding mutations in the leptin system.

Question

Answer

Mutations in the obese gene are a common cause of morbid obesity, where weight gain is evident from early childhood

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Mutations in the leptin receptor are associated with elevated circulating levels of leptin and late onset obesity

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Mutations in the leptin gene lead to elevated levels of circulating leptin, resulting in the development of leptin resistance

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Mutations in the leptin receptor are associated with elevated circulating levels of leptin and early-onset of obesity

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Leptin is secreted from adipose tissue and is a key hormone involved in the long...

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