After fusion with the terminal membrane and release of neurotransmitter, the vesicle membrane is recycled within the terminal.

Vesicle fusion with the terminal membrane can occur only in the region of the active zones.

Only vesicles bound to docking proteins can fuse with the pre-synaptic membrane.

Voltage-gated calcium channels are found across the entire surface of the terminal.

Calcium entry into the terminal occurs only through voltage-gated channels.