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Consider the following two ionisable groups positioned close to each other withi...

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Consider the following two ionisable groups positioned close to each other within a protein structure:

  • An arginine side chain (pKa = 12.5)
  • A glutamic acid side chain (pKa = 4.3)

Based on the pKa values of these functional groups and their charge states when they are ionised, select the correct statement below.

[Note that these statements are specifically referring to the attraction or repulsion of ionic interactions between these groups]

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