Defining a clinically relevant question → Searching for the best evidence → Critically appraising the evidence → Applying the evidence → Evaluating the performance of EBM

Searching for the best evidence → Defining a clinically relevant question → Applying the evidence → Critically appraising the evidence → Evaluating the performance of EBM

Defining a clinically relevant question → Searching for the best evidence → Critically appraising the evidence → Evaluating the performance of EBM → Applying the evidence

Evaluating the performance of EBM → Searching for the best evidence → Defining a clinically relevant question → Applying the evidence → Critically appraising the evidence