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A 35-year-old woman with pulmonary arterial hypertension (PAH) is using a combin...

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A 35-year-old woman with pulmonary arterial hypertension (PAH) is using a combined oral contraceptive (levonorgestrel/ethinylestradiol). She is receiving combination pharmacotherapy for PAH. Which of the following medications would necessitate additional contraceptive measures due to reduced effectiveness of hormonal contraception?

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