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Exemple de bariere biologice de izolare procariote (gazdă-vector) pot fi:
sisteme formate din bacteriile pUB110, pC194, pS194, pSA2100 și vectorii RUB 331, BGSC din familia Bacillaceae
Bacillus subtilis (tulpini RUB 331, BGSC 1S53) cu plasmidele pUB110, pC194, pS194, pSA2100, etc.
Escherichia coli K-12 (EK1) în combinaţie cu plasmide non-conjugante - pSC101, Co1E1, variante de bacteriofagi, fagul lambda
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