It reduces

food intake exclusively via the Y2 receptor, which is located only on NPY/AgRP

neurons in the hypothalamus.

Its primary

role is to increase the rate of gastric emptying post-prandially to facilitate

faster nutrient absorption in the duodenum.

It

is an incretin secreted from L-cells in the intestine that inhibits gastric

emptying and reduces food intake by directly stimulating POMC neurons in the arcuate

nucleus.

It is a

hunger-inducing hormone released from X/A-like cells in the stomach that

activates NPY/AgRP neurons via the GHSR receptor.