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Which of the following statements are correct:
I. The antigen binding site is only located within the heavy chain of the antibody
II. The antigen binding site is only located within the variable region of the antibody
III. The antigen binding site is only located within the light chain of the antibody
IV. The antigen binding site is only located within the constant region of the antibody
V. The antigen binding site is only located within the hinge region of the antibody