The same patient's serum bilirubin shows a predominantly indirect (unconjugated) elevation. According to the lecture, at what threshold of the direct (conjugated) bilirubin fraction as a proportion of the total bilirubin does hyperbilirubinemia ALMOST ALWAYS indicate hepatobiliary disease?

Question

Answer

Direct bilirubin greater than 5% of total bilirubin

Answer

Direct bilirubin in the 10–33% range — equal to the retained UGT1A1 activity percentage in Gilbert's syndrome

Answer

Direct bilirubin greater than 50% of total bilirubin

Answer

Direct bilirubin greater than 10% of total bilirubin

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Direct bilirubin greater than or equal to 15% of total bilirubin

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The same patient's serum bilirubin shows a predominantly indirect (unconjugated)...

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