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What mainly happens to chondrocytes during endochondral ossification in the limb...

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What mainly happens to chondrocytes during endochondral ossification in the limbs?

They stop proliferating and become mesenchymal stem cells

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They move into blood vessels and are excreted in the kidney

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They are deprived of nutrients and undergo apoptosis

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They differentiate into osteoclasts and produce bone

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