During tumour progression, epithelial
cancer cells acquire the ability to detach from neighbouring cells, invade
surrounding tissues, and migrate toward blood vessels. Molecular analysis shows
suppression of proteins that normally maintain epithelial cell adhesion.

Which molecular change most directly
explains this phenotype?

Question

During tumour progression, epithelial
cancer cells acquire the ability to detach from neighbouring cells, invade
surrounding tissues, and migrate toward blood vessels. Molecular analysis shows
suppression of proteins that normally maintain epithelial cell adhesion.

Which molecular change most directly
explains this phenotype?

Accepted Answer

Loss
of E-cadherin that normally maintains epithelial tissue architecture

Answer

Up-regulation of
telomerase that extends telomeres and prevents cellular senescence

Answer

Increased expression
of VEGF that stimulates new blood vessel formation

Answer

Activation of
Cytochrome C involved in apoptosis signalling

Crowdly

During tumour progression, epithelial cancer cells acquire the ability to detac...

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